addicted to benzos?


Q: What makes a person get addicted to benzos?

A: Tolerance.

The main problem of the chronic use of benzodiazepines (i.e., benzos) is the development of tolerance and dependence. Tolerance manifests itself as diminished pharmacological effect and develops relatively quickly to the sedative, hypnotic, anticonvulsant, and muscle relaxant actions of benzodiazepines. Tolerance to anti-anxiety effects develops more slowly with little evidence of continued effectiveness beyond four to six months of continued use.[14] In general, tolerance to the amnesic effects does not occur.[99] However, controversy exists as to tolerance to the anxiolytic effects with some evidence that benzodiazepines retain efficacy[125] and opposing evidence from a systematic review of the literature that tolerance frequently occurs[25][32] and some evidence that anxiety may worsen with long-term use.[14] The question of tolerance to the amnesic effects of benzodiazepines is, likewise, unclear.[126] Some evidence suggests that partial tolerance does develop, and that, “memory impairment is limited to a narrow window within 90 minutes after each dose”.[127]


AND THAT’S THE TRUTH


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